Technology and the expansion of human capabilities are intimately related. This chapter discusses an influential philosophical framework that attaches central moral importance to human capabilities, namely, the so-called capability approach, and explains in which ways it has relevance for design. A distinction will be drawn between two different, although related, design applications of the capability approach. Firstly, in the “narrow” usage, the capability approach is seen as presenting a proper conceptualization of individual well-being, namely, in terms of the capabilities that a person has. The aim of design is then to contribute to the expansion of these capabilities, to which I refer as design for capabilities. I will discuss two challenges for design for capabilities, namely, an epistemological and an aggregation challenge. Secondly, in the “broad” usage, the capability approach is seen as a source of insight and inspiration for taking a broader range of values and concerns into account in design, most importantly agency and justice. From this perspective, so it is argued, strong parallels can be drawn with participatory design and universal design. In reality both the narrow and the broad usage of the capability approach in design should go hand in hand. The chapter ends with some reflections on the challenges ahead in making the philosophical literature on the capability approach accessible to and usable by designers.