On the basis of the recently proposed new fundamental equation of mathematical biophysics, a suggestion is made for a theory of the formation of a primitive cell from nonliving material. The discussion includes a suggestion for a quantitative formulation of the degree of biological organization. It is shown that according to the fundamental equation of mathematical biophysics, organization of the nonliving material may spontaneously increase under certain conditions, leading to a formation of a primitive organism. This process however, is a very slow one, requiring time intervals of several years or even decades. This may account for the failure in observing or artificially producing spontaneous generation.